For instance, in the course of the epithelial to mesenchymal transition (EMT), where polarized epithelial cells are transferred toward more motile mesenchymal cells during biological processes including embryogenesis and the malignant progression of cancer (Chen et al., 2017), laminin-rich extracellular matrix is able to abolish EMT, whereas fibronectin-rich extracellular matrix fosters the transformation of it (Chen et al., 2013). This evidence concerns the gene FN1 and cancer.