miR-210 is strongly connected to hypoxia as it is induced by the absence of functional von Hippel–Lindau (VHL) tumor suppressor gene, which is frequently encountered in RCC tumorigenesis (Shen and Kaelin, 2013), and by increasing hypoxia-inducible factor (HIF) activity (Neal et al., 2010; McCormick et al., 2013; Liu L. L. et al., 2017). Here, VHL is linked to renal cell carcinoma.