As represented in Table 2, depth of tumor invasion (T3/4), lymph node metastasis (N1/2), distant metastasis, TNM stage (III/IV), neural invasion, high expression of FBG, high expression of LDH, high expression of FMN, high expression of both B7-H3 and FMN, low expression of B7-H3 and high expression of FBG, low expression of B7-H3 and high expression of LDH, low expression of B7-H3 and high expression of FMN were highly correlated with the OS of patients with CRC. Here, FMN1 is linked to metastatic malignant neoplasm in the lymph nodes.