As a result, 5% BIRC3, 7% BTN3A1, 2% CSF2RB, 4% GIMAP7, 6% GZMB, 5% HCLS1, 7% LCP2, and 8% SELL were altered in six types of genetic alterations, including missense mutation, truncating mutation (putative driver), truncating mutation (unknown significance), amplification, deep deletion, and mRNA high, in the queried TCGA breast cancer samples (Figure 8A). The gene discussed is GZMB; the disease is breast cancer.