SPTSSA and nonpapillary renal cell carcinoma: In a clear cell renal cell carcinoma (ccRCC) study, bioinformatics analysis revealed that 10 genes, including SPTSSA, significantly coregulated ccRCC with SPTLC1, and the low expression of SPTLC1 was significantly correlated with the disease progression and poor prognosis of ccRCC (54).