Univariate and multivariate analysis using the COX model showed that the grade of PDAC (hazard ratio [HR]: 2.924, 95% confidence interval [CI]: 1.291–6.621), tumor size (HR: 3.900, 95% CI: 1.114–13.645) and the expression level of SYPL1 (HR: 2.807, 95% CI: 1.204–6.543) were independent prognostic factors for patients in the SYSUCC (Table 2). The gene discussed is SYPL1; the disease is neoplasm.