recently provided a way to extract melanoma specific exosomes from plasma samples using a combination of isolation methods including size exclusion chromatography and magnetic beads conjugated with antichondroitin surface proteoglycan 4 (CSPG4), which targets melanoma cells and exosomes.[28] They verified the specificity of isolated exosomes using FACS and showed that the subset of EVs they captured were melanoma specific and related to immune suppression. The gene discussed is CSPG4; the disease is melanoma.