Data from Evans blue/TTC staining showed that under the same degrees of AAR, TBC1D15 attenuated myocardial infarct size following 3-day MI (24.44 ± 1.99 vs. 44.52 ± 3.88 from MI, P < 0.05), the effect of which was nullified by either TBC1D15 mutant (Figure S7D-F). Here, TBC1D15 is linked to myocardial infarction.