Along the same line, LVESD (3.306 ± 0.254 vs. 1.964 ± 0.100 from Sham, P < 0.05) and LVESV (46.40 ± 8.61 vs. 12.44 ± 1.59 from Sham, P < 0.05) were dramatically enhanced following MI procedure, the effect of which was partially reversed by TBC1D15 overexpression (2.469 ± 0.158 vs. 3.306 ± 0.254 from MI, P < 0.05 for LVESD; 22.42 ± 3.77 vs. 46.40 ± 8.61 from MI, P < 0.05 for LVESV) (Figure S2C-D). Here, TBC1D15 is linked to myocardial infarction.