Linear regression analysis of the curves showed no difference between the slopes but significant differences in the intercepts (p = 0.007) indicating that the rate of release of luciferin from MBs was constant but that there was greater initial delivery of luciferin to the tumor with VEGFR2 targeting and ensuing uptake throughout the tumor due to its highly water soluble nature and the inherent leakiness of the luciferin liposomes. Here, KDR is linked to neoplasm.