Subtracted molecular signals (SMS) equating to the signal from VEGFR2-targeted MBs were higher (but not significantly different) in smaller than larger tumors (11 ± 2.4 versus 6 ± 2.5, respectively, Figure 1C and Figure S1 C-D) suggesting that in this model, there was sufficient VEGFR2 across all tumor sizes for it to be actively targeted by thMBs. Here, KDR is linked to neoplasm.