Multiple regression analysis was run to predict prostate-specific antigen levels > 0 ng/mL as an indicator for risk of prostate cancer development from schistosomiasis infection status, history of schistosomiasis infection and haematuria intensity predicted prostate-specific antigen levels > 0 ng/mL F (3, 184) = 3.872, P (0.010) < 0.05, R2 = 0.059. This evidence concerns the gene KLK3 and Familial prostate cancer.