CXCL8 and Autoimmunity: LPS correlated positively with IL-6 (p = 0.028, r = 0.216), a central cytokine in the pathogenesis of several autoimmune disorders as well as of inflammation in CVID (4), but not did not correlate significantly with IL-8 (p = 0.192, rho = 0.129), IL-12 (p = 0.064, rho = 0.182), or TNFα (p = 0.143, rho = 0.145).