This is an autosomal recessive inherited disorder and the genetic variants of this patient were p.S267Lfs*20 and p.G239D of ACP5. For the PRAAS/CANDLE patient, the most prominent characteristic was lypodystrophy, other clinical features included fever, rash, PAH, arthritis, intracranial calcification, uveitis, loss of hearing, and growth retardation. Here, ACP5 is linked to uveitis.