TGFB1 and neoplasm: The previously described regulatory γδ T cells can contribute to the establishment of an immunosuppressive microenvironment and to the inhibition of the anti-tumor response in different manners, for instance by producing inhibitory factors (e.g., IL-10, IL-8, TGF-β and adenosine) or by recruiting immunosuppressive cells (e.g., MDSCs and neutrophils).