CSF3R and neoplasm: As in the tumor tissues, IFNγ, IL-10, IL-17A, and IL-4 were measured and similar to tumor tissues, in vitro culture of T cells were found to have significantly increased levels of IFNγ and IL-17A, with G-CSFR−/− CD4+ T cells, while IL-10 and IL-4 levels were decreased compared to WT (Figure 2B).