More interestingly, inspired by two cases of THSD7A-associated MN accompanied by angiolymphoid hyperplasia with eosinophilia (ALHE), the researchers assumed that vascular endothelial growth factor A (VEGF-A) up-regulated the expression of THSD7A in endothelial cells in vitro (38). The gene discussed is VEGFA; the disease is Increased total eosinophil count.