The mean age at diagnosis of renal angiomyolipomas was 13.3 years (median, 9 years, range <1–59 years) in patients with a TSC2 mutations, while it was 22.5 years (median 21 years, range <1–60 years) in those with a TSC1 mutations. Here, TSC1 is linked to kidney angiomyolipoma.