Further applications beyond PD may be also considered, as functional associations between Miro1 and key proteins causative of other neurodegenerative diseases, such as Alzheimer's disease (142, 143), amyotrophic lateral sclerosis (144, 145), and Charcot–Marie–Tooth disease (146), were discovered during the past years. The gene discussed is RHOT1; the disease is Parkinson disease.