This interplay came into the focus of PD research, since several PD-associated proteins were recently identified as regulators of mitochondria-ER contact sites (MERCs), i.e., PINK1, Parkin, LRRK2, or α-synuclein (17–20), all of which are also interacting with Miro1 (7, 11, 12, 21). Here, PRKN is linked to Parkinson disease.