INS and diabetic cardiomyopathy: While the accumulation of TAGs, ceramides, diacylglycerols, and other lipid intermediates may promote myocardial insulin resistance, lipotoxicity, and cardiac myocyte apoptosis in diabetic cardiomyopathy, we encourage the reader to refer to the many excellent reviews already published on this topic (van de Weijer et al., 2011; D’Souza et al., 2016; Zlobine et al., 2016).