PPARA and dilated cardiomyopathy: Intriguingly, treatment of 3-month-old TazKD mice with the pan-PPAR agonist (primarily PPARα), bezafibrate, via supplementation in the diet (0.05% weight/weight) for 4 months, prevented the development of dilated cardiomyopathy and systolic dysfunction (Schafer et al., 2018).