Supporting this, it has been reported that upregulation of Snail, a major regulator of EMT, correlated with the downregulation of critical genes involved in FAO expression in hepatocellular carcinomas (Tanaka et al., 2013); pharmacological inhibition of FAO reverses Snail-mediated metabolic reprogramming in vivo and progression of breast cancer (Yang et al., 2020). This evidence concerns the gene SNAI1 and breast carcinoma.