Severe congenital neutropenia is not the only inherited BMF syndrome with predisposition to MDS and AML; however, we believe that SCN provides the most robust and accurate disease to model because acquisition of CSF3R mutation is so common (70-80%) as a secondary hit (see discussion of sources in Wojdyla et al., 2019). The gene discussed is CSF3R; the disease is myelodysplastic syndrome.