The Nod-like receptor family protein 3 (NLRP3) inflammasome is a cytosolic protein complex composed of NLRP3, the adaptor protein apoptosis-associated speck-like protein with a CARD domain (ASC), and caspase 1, which are rapidly assembled in response to both infection with pathogens and endogenous “danger signals” such as monosodium urate, alum, silica, reactive oxygen species, amyloid β, and cholesterol (Duewell et al., 2010; Spreafico et al., 2010; Tschopp and Schroder, 2010; Peeters et al., 2013; Cho et al., 2014; Shaw et al., 2014; Kong et al., 2017). This evidence concerns the gene NLRP3 and infection.