FN1 and neoplasm: CAFs express a variety of integrins, such as integrin αvβ3 (Attieh et al., 2017), α5β1 (Erdogan et al., 2017), and α11 (Primac et al., 2019; Zeltz et al., 2019), that participate in the assembly of fibronectin in ECM and facilitate the conversion of fibronectin matrix to fibronectin and the deposition of CAFs on tumor stroma (Cavaco et al., 2018).