Cluster #0 (atherosclerotic cardiovascular event), with the warmest color and largest nodes scattered on the timeline, contained 7 of the 10 most frequently cited references, namely articles by Zinman B (2015) (Zinman et al., 2015), Sarafidis PA (Sarafidis and Tsapas, 2016), Neal B (2017) (Neal et al., 2017), Wanner C (2016) (Wanner et al., 2016), White WB (White et al., 2013), Pfeffer MA (Pfeffer et al., 2015) and Wiviott SD (2019) (Wiviott et al., 2019), who assessed the effects of SGLT2 inhibitors and GLP-1 on atherosclerotic CV outcomes in patients with T2DM. Here, SLC5A2 is linked to type 2 diabetes mellitus.