This result might have been obtained because edema was easy to detect during examination and because Ro52 positivity reflects systemic edema.(36,37) It was reported that Ro52 positivity is not specific to myositis and is more prevalent in other CTDs.(16) This could be another reason for the lack of specific symptoms other than IP among Ro52 positive patients. The gene discussed is TRIM21; the disease is incontinentia pigmenti.