In addition, quercetin inhibits growth of hepatocellular carcinoma by apoptosis induction in part via autophagy stimulation in mice.(28) Consistent with those previous studies, our results revealed that, autophagy inhibitor Baf.A1 or ATG5-shRNA could avert the effect of quercetin on cell death, which indicated that quercetin-induced autophagic cell death in OS cells. Here, ATG5 is linked to hepatocellular carcinoma.