The frequency of ApoE genotypes, including ε2/ ε2, ε2/ ε3, ε2/ ε4, ε3/ ε3, ε3/ ε4, and ε4/ ε4, was not significantly different between AD-A and AD-NA groups (P>0.05) (Table 2). The gene discussed is APOE; the disease is Alzheimer disease.