HeLa and SiHa cells were treated with RES, and the expression levels of epithelial‐mesenchymal transition (EMT) molecular markers, such as N‐cadherin, E‐cadherin, and vimentin, and extracellular matrix (ECM) degradation enzymes, such as MMP‐3 and MMP‐13, which indicated the invasion potential of cervical cancer cells were determined. The gene discussed is VIM; the disease is cervical cancer.