Independent groups have identified genes that consistently accounted for pathogenic and likely pathogenic variants for DCM: TTN, MYH7, DSP, SCN5A, LMNA, TPM1, TNNC1, TNNT2, BAG3, PLN, RBM20, LDB3, DMD, DES, ACTC1, NEXN, and VCL [5, 38–41]. This evidence concerns the gene SCN5A and familial dilated cardiomyopathy.