DSP and Ventricular arrhythmia: A large case series of 107 individuals with DSP pathogenic variants (105 with truncating variants) revealed left ventricular phenotypes in 86%, including dilation, delayed enhancement, and myocardial injury; while ventricular arrhythmias were found in 56% of individuals with DSP mutations, diagnostic criteria for ARVC were met less frequently for DSP positive as compared with PKP2-positive individuals [37•].