Some of the mouse proteins, DA between CKD and CKDRS were also found in our previous study, for example, mucin (playing an important role in maintaining the integrity of the intestinal mucosal barrier), angiotensin‐converting enzyme (CKD biomarker), annexins A2 and A4 (cellular membrane repair) (Zybailov et al., 2019). Here, ACE is linked to chronic kidney disease.