CAV1 and odontogenic neoplasm: However, to the best of our knowledge, this is the first study whose objective was to evaluate caveolin-1 expression by immunohistochemistry in a considerable number of AMs (also analyzing the cav-1 gene transcript expression by qRT-PCR) and in human tooth germ (TG) and ameloblastic carcinoma (AC), which is the malignant counterpart of AM; although it is rare, AC is the most frequent malignant odontogenic tumor and presents higher recurrence rates and metastatic potential than other malignant odontogenic tumors (9).