METTL3 expression significantly correlated with AJCC staging (the eighth edition, P = 0.0056), lymph node metastasis (P = 0.0251), and vascular invasion (P = 0.0346), but did not correlate with gender, age, differentiation, and tumor invasion (Table 1, Fig. 1g). This evidence concerns the gene METTL3 and neoplasm.