In SLE, a number of different T cell disturbances have been described, which can contribute to the generation of autoreactive T cells, aberrant cytokine production and impaired T regulatory cell function.32 Besides the direct involvement of pathways connected to Th1 and Th2 cells, we noticed association signals from two pathways related to interleukin 17 (IL-17). The gene discussed is IL17A; the disease is systemic lupus erythematosus.