And a better predicting power from EN-RAGE/sRAGE was generated with AUC of 0.83, 76.1% sensitivity, 81% specificity for AIH patients with remission after prednisolone plus azathioprine treatment, suggesting that EN-RAGE/sRAGE may be potential candidate for the evaluation of therapeutic response in AIH patients. This evidence concerns the gene AGER and autoimmune hepatitis.