▪ Tocilizumab (anti IL-6) in patients with all the following criteria: IL6 > 5 x ULN; transaminase levels lower than × 5 upper limit of normal; neutrophils > 500 cell/mm3; platelets > 50,000 cell/mm3; no clinical signs of sepsis; no diverticulitis nor bowel perforation; no systemic or cutaneous infection; no other biologics. The gene discussed is IL6; the disease is diverticulitis.