The univariable analysis demonstrated that BMI, jaundice, lymph node metastasis, intrahepatic involvement, extrahepatic involvement, tumor differentiation, radical cure, R0, TG, HDL, TC/HDL, TG/HDL, ApoA1, ApoB, lipoprotein, albumin, GGT, ALP, TBIL, CA199 were associated with OS (P < 0.05) (Table 2). The gene discussed is APOB; the disease is metastatic malignant neoplasm in the lymph nodes.