Although non-Löfgren’s sarcoidosis patients at first showed no difference between healthy controls and Löfgren’s syndrome patients in CD8+ T-cell-mediated lysis of target cells, after pre-stimulation with the T-cell-activating lectin phytohemagglutinin A and the mitogenic cytokine IL-2, CD8+ T lymphocytes from non-Löfgren’s syndrome sarcoidosis patients exhibited significantly higher target cell lysis rates compared to pre-stimulated CD8+ T lymphocytes in healthy controls and Löfgren’s syndrome patients [67,68,69]. The gene discussed is CD8A; the disease is sarcoidosis.