Initially, the expression of SEMA3(A-G), NRP1, NRP2, PLXNA2, PLXND1, CDH1, CDH2, ITGB1, ITGB3, ITGA5, ITGAV, KDR, and VEGFA genes at mRNA level were compared between astrocytoma and healthy human brain (control) samples. This evidence concerns the gene ITGAV and astrocytoma (excluding glioblastoma).