By summarizing results, we noticed that SEMA3B, SEMA3D, SEMA3F, SEMA3G, NRP1, PLXNA2, ITGB3, ITGA5, and VEGFA were significantly associated with 4 clinicopathological characteristics (age, tumor grade, IDH mutation and survival time), which were closely related to unfavorable patient outcomes (genes in bold in Table 1). The gene discussed is SEMA3D; the disease is neoplasm.