In relation to the malignancy grade of the tumor, mRNA levels of SEMA3B, SEMA3C, SEMA3D, SEMA3G, PLXNA2, and CDH1 decreased while mRNA levels of SEMA3F, NRP1, ITGB3, ITGA5, and VEGFA increased with the increase of the tumor malignancy (p < 0.05) (Table 1). The gene discussed is SEMA3B; the disease is neoplasm.