The decrease in tumor expression of p-class I PI3K/p-mTOR/p-p70S6K and increase of p-ERK (Figure 6F) validated the results using bioinformatics analysis and confirmed the observation in vitro (Figure 7), further highlighting the role of mutant HRAS in cisplatin sensitivity of T24 xenografts in response to pterostilbene. Here, RPS6KB1 is linked to neoplasm.