It is noteworthy that two cisplatin-resistant cell lines (VMCUB1 and SW1710) with a lower expression level of HRAS were resistant to pterostilbene, and the cisplatin-resistant cell line expressing the highest level of HRAS (HT1376) was sensitive to pterostilbene (Figure 1D and Figure 2C), suggesting the role of HRAS gene expression in bladder cancer cells sensitized to cisplatin by pterostilbene. This evidence concerns the gene HRAS and urinary bladder cancer.