Considering that AMD-related SNPs in age-related maculopathy susceptibility 2 [24] and complement factor H [24, 25] are related to choroidal vascular hyperpermeability, and observed in eyes with relatively shorter ALs [24], AMD-related SNPs and AL determinant factors could have the possibility of genetic linkages, although further studies are required. This evidence concerns the gene CFH and age-related macular degeneration.