WEE1 and non-small cell lung carcinoma: The treatment of non-small cell lung cancer cells (A549 and NCI-H1975) with Nag-E was found to induce G2/M phase cell cycle arrest through down-regulation of the protein kinase Wee1, the protein Cyclin B1 and reduction of the phosphorylation of cyclin-dependent kinases cdc2 and cdc25C.