LMNB1 and adult-onset autosomal dominant demyelinating leukodystrophy: The diagnosis of ADLD is supported by the combination of patient’s clinical history, physical examinations, magnetic resonance imaging (MRI) showing symmetrical cerebral white matter hyperintensities from the motor cortex to the medulla oblongata and involvement of the upper and middle cerebellar peduncles and confirmed by Lamin B1 (LMNB1) gene analysis [1, 13, 16, 18].