Recently, it was shown that GSDMD‐dependent pyroptosis in intestinal epithelial cells, which is triggered downstream of never in mitosis gene A (NIMA)‐related kinase 7 (NEK7)‐mediated NLRP3 inflammasome activation, is implicated in the pathogenesis of IBD in vitro and in vivo.83 Here, GSDMD is linked to inflammatory bowel disease.