SIGLEC15 and neoplasm: Certain well‐known inhibitors, such as B7‐H3 (cluster of different, CD276), lymphocyte‐activated gene 3 (LAG3), and vascular endothelial growth factor (VEGFB), and a novel immune suppressor, sialic acid‐binding Ig‐like lectin (Siglec‐15),18 were significantly upregulated in tumor tissues compared to corresponding NATs, which might suggest an immune evasion of SCCE (Figure 2a, Supplementary figure 4).