miR-12116 and CMTM2 expression in the 40 specimens of GC tissues were detected via qRT-PCR, and the current results demonstrated that, compared with that in paired adjacent nontumor tissues, miR-12116 expression was significantly higher (n=40, P < 0.01; Figure 6B) and CMTM2 expression was significantly lower in GC tissues (n=40, P < 0.01; Figure 6C). This evidence concerns the gene CMTM2 and gastric cancer.