LMNA and microcephaly: Lastly, we examined the cellular distribution of GFP-lamin B fusion proteins containing microcephaly variants, in a similar manner to that done previously for LMNA variants.13 Cells expressing the LMNB1/B2 variants frequently contained nuclear aggregates and/or significantly altered nuclear morphology in comparison to cells expressing wild-type GFP-LMNB1/2 (Fig. S2, Tables S8 and S9).