As expected, known tumour suppressor or oncogenic genes such as TP53 (found mutated in 16/35 patients), PIK3CA (7/35), BRCA1 (4/35), NF1 (3/35), EGFR (3/35), ERBB2 (3/35), ATM (3/35) or RET (3/35) are found recurrently mutated in our cohort. This evidence concerns the gene PIK3CA and neoplasm.