APOE and Alzheimer disease: The sTREM2 x ApoE4 interaction remained significant when tested in MCI (F = 7.72, p = 0.006 Cohens f2 = 0.147), but was non-significant when tested in CN (p = 0.35), AD (p = 0.20) or Aβ + only (F = 2.43, p = 0.120, Fig. 2f).