In addition, positive WTX expression was observed for 15.2% (15/99) of groups with lymph node metastasis and 43.6% (17/39) of groups without lymph node metastasis (P < 0.001, Fig. 1d and Table 1), suggesting that WTX expression is negatively correlated with lymph node metastasis. The gene discussed is AMER1; the disease is metastatic malignant neoplasm in the lymph nodes.