Positive IHC staining of WTX was observed in 47.8% (11/23), 26.8% (15/56), and 13.4% (11/82) of well-, moderately, and poorly differentiated tumours, respectively (P = 0.011, Fig. 1e and Table 1), indicating that WTX expression is positively correlated with GC differentiation. The gene discussed is AMER1; the disease is neoplasm.