In vivo mouse experiments found that siRNA knockdown of Myl9 expression reduces invasion and lung colonization of two highly metastatic tumor cell lines, human MDA‐MB‐231 breast carcinoma and mouse B16F2 melanoma, suggesting an important role for Myl9's cytoskeletal functions in metastasis (Medjkane et al., 2009). This evidence concerns the gene MYL9 and breast carcinoma.