Inhibiting PLXNB2 suppresses the development of xenograft tumors in mice (Yu et al., 2017)Inhibiting PLXNB2 makes prostate cancer stem cells more sensitive to chemotherapy (Li et al., 2020)Motor sensory recovery following spinal cord injury is impaired in mice lacking Plxnb2 in myeloid cells (X. Zhou et al., 2020). This evidence concerns the gene PLXNB2 and Familial prostate cancer.