NAB1 is upregulated in human heart failure and mice overexpressing Nab1 are protected from induced hypertrophy (Buitrago et al., 2005)In dogs with moderate heart failure, treatment with rosuvastatin reduces the expression of NAB1 in left ventricular tissue (Zaca et al., 2012)A single nucleotide polymorphism in NAB1 is associated with systemic lupus erythematosus, rheumatoid arthritis, systemic sclerosis, and idiopathic inflammatory myopathies (Acosta‐Herrera et al., 2019). This evidence concerns the gene NAB1 and heart failure.